Publications
Schneider L, Guo YK, Birch D, Sarkies P. Network-based visualisation reveals new insights into transposable element diversity. Mol Syst Biol 2021 Jun; 17(6):e9600. doi: 10.15252/msb.20209600
Berkyurek AC, Furlan G, Lampersberger L, Beltran T, Weick EM, Nischwitz E, Cunha Navarro I, Braukmann F, Akay A, Price J, Butter F, Sarkies P, Miska EA. The RNA polymerase II subunit RPB-9 recruits the integrator complex to terminate Caenorhabditis elegans piRNA transcription. EMBO J. 2021 Mar 1;40 (5):e105565. doi: 10.15252/embj.2020105565.
Hagen J, Sarkies P, Selkirk ME. Lentiviral transduction facilitates RNA interference in the nematode parasite Nippostrongylus brasiliensis. PLoS Pathog. 2021 Jan 26;17(1):e1009286. doi: 10.1371/journal.ppat.1009286.
Beltran T, Pahita E, Ghosh S, Lenhard B, Sarkies P. Integrator is recruited to promoter-proximally paused RNA Pol II to generate Caenorhabditis elegans piRNA precursors. EMBO J. 2021 Mar 1;40(5):e105564. doi: 10.15252/embj.2020105564.
Bergthorsson U, Sheeba CJ, Konrad A, Belicard T, Beltran T, Katju V, Sarkies P. Long-term experimental evolution reveals purifying selection on piRNA-mediated control of transposable element expression. BMC Biol. 2020 Nov 6;18(1):162. doi: 10.1186/s12915-020-00897-y.
Dabin LC, Guntoro F, Campbell T, Bélicard T, Smith AR, Smith RG, Raybould R, Schott JM, Lunnon K, Sarkies P, Collinge J, Mead S, Viré E. Altered DNA methylation profiles in blood from patients with sporadic Creutzfeldt-Jakob disease. Acta Neuropathol. 2020 Dec;140(6):863-879. doi: 10.1007/s00401-020-02224-9.
Beltran T, Shahrezaei V, Katju V, Sarkies P. Epimutations driven by small RNAs arise frequently but most have limited duration in Caenorhabditis elegans. Nat Ecol Evol. 2020 Nov;4(11):1539-1548. doi: 10.1038/s41559-020-01293-z.
Gasparetto M, Payne F, Nayak K, Kraiczy J, Glemas C, Philip-McKenzie Y, Ross A, Edgar RD, Zerbino DR, Salvestrini C, Torrente F, Ventham NT, Kalla R, Satsangi J, Sarkies P, Heuschkel R, Zilbauer M. Transcription and DNA Methylation Patterns of Blood-Derived CD8+ T Cells Are Associated With Age and Inflammatory Bowel Disease But Do Not Predict Prognosis. Gastroenterology. 2021 Jan;160(1):232-244.e7. doi: 10.1053/j.gastro.2020.08.017.
Taylor PJ, Hagen J, Faruqu FN, Al-Jamal KT, Quigley B, Beeby M, Selkirk ME, Sarkies P. Trichinella spiralis secretes abundant unencapsulated small RNAs with potential effects on host gene expression. Int J Parasitol. 2020 Aug;50(9):697-705. doi: 10.1016/j.ijpara.2020.05.008.
Lewis SH, Ross L, Bain SA, Pahita E, Smith SA, Cordaux R, Miska EA, Lenhard B, Jiggins FM, Sarkies P. ------Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods. PLoS Genet. 2020 Jun 25;16(6):e1008864. doi: 10.1371/journal.pgen.1008864.
Drinnenberg IA, Berger F, Elsässer SJ, Andersen PR, Ausió J, Bickmore WA, Blackwell AR, Erwin DH, Gahan JM, Gaut BS, Harvey ZH, Henikoff S, Kao JY, Kurdistani SK, Lemos B, Levine MT, Luger K, Malik HS, Martín-Durán JM, Peichel CL, Renfree MB, Rutowicz K, Sarkies P, Schmitz RJ, Technau U, Thornton JW, Warnecke T, Wolfe KH. EvoChromo: towards a synthesis of chromatin biology and evolution. Development. 2019 Sep 26;146(19):dev178962. doi: 10.1242/dev.178962.